Decreasing SHBG According to studies, formestane can lower SHBG up to 34%, which will increase free testosterone levels. SHBG (sex hormone binding globulin) is a protein that binds to sex steroids, and renders them inactive, for as long as SHBG is bound to them. There is a difference between ‘free’ testosterone, and ‘bound’ testosterone. Free testosterone is what matters, so lowering SHBG will increase ‘free’ testosterone. Higher testosterone means more strength, muscle mass, less body fat, better sense of well being, and libido. Aromatase Inhibitor Many anabolic steroids aromatize in the body into estrogen. The most common are deca durabolin, equipoise, testosterone, and dbol. If an AI is not used, estrogen will increase and potentially cause major problems with estrogenic side effects. The most common side effects of estrogen are gynecomastia (bitch tits), excessive water retention (moon face), high blood pressure (hypertension), and insomnia. In addition, coming off cycle with estrogen levels that are too high can hinder recovery of the body’s HPTA, causing gains on cycle to be lost. Formestane, while being used, will permanently disable the aromatase enzyme, so that it does not rebound after cycle. Other AI’s, such as letrozole and arimidex will not stop estrogen rebound. Formestane Dosage